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Roizman, Bernard

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Item Type	Name
Concept	RNA, Messenger
Academic Article	Redefining virology.
Academic Article	An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.
Academic Article	Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection.
Academic Article	RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions.
Academic Article	The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific.
Academic Article	The UL41 protein of herpes simplex virus mediates selective stabilization or degradation of cellular mRNAs.
Academic Article	The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene.
Academic Article	Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions.
Academic Article	The stress-inducible immediate-early responsive gene IEX-1 is activated in cells infected with herpes simplex virus 1, but several viral mechanisms, including 3' degradation of its RNA, preclude expression of the gene.
Academic Article	The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins.
Academic Article	Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs.
Academic Article	State and role of SRC family kinases in replication of herpes simplex virus 1.
Academic Article	The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A.
Academic Article	Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase.
Academic Article	Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes.
Academic Article	Antisense RNA directed to the human papillomavirus type 16 E7 mRNA from herpes simplex virus type 1 derived vectors is expressed in CaSki cells and downregulates E7 mRNA.
Academic Article	Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNA.
Academic Article	The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes.
Academic Article	Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells.
Academic Article	Herpes simplex virus 1 precludes replenishment of the short-lived receptor of tumor necrosis factor alpha by virion host shutoff-dependent degradation of its mRNA.
Academic Article	The herpes simplex virus host shutoff RNase degrades cellular and viral mRNAs made before infection but not viral mRNA made after infection.
Academic Article	Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs.
Academic Article	The nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAs.
Academic Article	Tristetraprolin Recruits the Herpes Simplex Virion Host Shutoff RNase to AU-Rich Elements in Stress Response mRNAs To Enable Their Cleavage.
Academic Article	Herpes Simplex Virus 1 MicroRNA miR-H28 Exported to Uninfected Cells in Exosomes Restricts Cell-to-Cell Virus Spread by Inducing Gamma Interferon mRNA.
Academic Article	hnRNPA2B1 Associated with Recruitment of RNA into Exosomes Plays a Key Role in Herpes Simplex Virus 1 Release from Infected Cells.
Grant	DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
Grant	Selective Degradation of mRNA by Herpes Simplex Virus 1
Grant	Dissection of the Functions of Herpes Simplex Virus ICPO
Grant	MECHANISMS OF VIRAL INFECTION IN RELATION TO CANCER
Grant	UCCRC: VIRAL ONCOLOGY PROGRAM
Grant	MECHANISMS OF VIRAL INFECTION IN RELATION TO CANCER

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RNA Messenger